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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: TFAP2{A,C}.p2

Z-value: 2.659

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_+_43299277	7.982	NM_005892	FMNL1	formin-like 1
chr11_-_1593149	6.646	NM_004420	DUSP8	dual specificity phosphatase 8
chr19_+_42788605	4.386	NM_015125	CIC	capicua homolog (Drosophila)
chr5_+_172483285	4.302	NM_001168393 NM_001168394 NM_153607	C5orf41	chromosome 5 open reading frame 41
chr7_-_100493481	4.251	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr6_+_17281773	3.914	NM_001143942	RBM24	RNA binding motif protein 24
chr19_+_7660698	3.603	NM_001080429 NM_020902	CAMSAP3	calmodulin regulated spectrin-associated protein family, member 3
chr1_+_178063272	3.580		RASAL2	RAS protein activator like 2
chr12_-_117319231	3.573	NM_003806	HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)
chr11_-_78128765	3.563		GAB2	GRB2-associated binding protein 2
chr17_+_17584772	3.563	NM_030665	RAI1	retinoic acid induced 1
chr9_-_110251308	3.499		KLF4	Kruppel-like factor 4 (gut)
chr7_+_1570321	3.482	NM_002360	MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr6_-_143266283	3.429	NM_006734	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2
chr10_-_77159851	3.343		ZNF503	zinc finger protein 503
chr1_+_201857997	3.330		SHISA4	shisa homolog 4 (Xenopus laevis)
chr1_+_16010838	3.307		PLEKHM2	pleckstrin homology domain containing, family M (with RUN domain) member 2
chr10_-_77161424	3.264	NM_032772	ZNF503	zinc finger protein 503
chr19_+_40697516	3.248	NM_002446	MAP3K10	mitogen-activated protein kinase kinase kinase 10
chr10_-_77161136	3.231		ZNF503	zinc finger protein 503
chr2_-_145274916	3.186		ZEB2	zinc finger E-box binding homeobox 2
chr22_-_46933066	3.177	NM_014246	CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr12_-_123635284	3.099		PITPNM2	phosphatidylinositol transfer protein, membrane-associated 2
chr19_+_13906207	3.075	NM_023072	ZSWIM4	zinc finger, SWIM-type containing 4
chr4_+_139936938	3.068	NM_012118	CCRN4L	CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr11_+_61447816	2.965	NM_006133	DAGLA	diacylglycerol lipase, alpha
chr7_+_100081549	2.958	NM_173564	NYAP1	neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1
chr19_-_1848447	2.938	NM_020695	REXO1	REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr20_+_2673193	2.924	NM_001110514	EBF4	early B-cell factor 4
chr11_+_46299585	2.923		CREB3L1	cAMP responsive element binding protein 3-like 1
chr10_-_3827418	2.915	NM_001160124 NM_001160125 NM_001300	KLF6	Kruppel-like factor 6
chr15_-_60884615	2.899	NM_134262	RORA	RAR-related orphan receptor A
chr19_+_34972866	2.882	NM_001080436	WTIP	Wilms tumor 1 interacting protein
chr3_+_184097860	2.852	NM_003741	CHRD	chordin
chrX_+_49126480	2.814		PPP1R3F	protein phosphatase 1, regulatory subunit 3F
chr1_+_16010816	2.805	NM_015164	PLEKHM2	pleckstrin homology domain containing, family M (with RUN domain) member 2
chr19_+_4969126	2.800		KDM4B	lysine (K)-specific demethylase 4B
chr9_+_35605275	2.796	NM_006285	TESK1	testis-specific kinase 1
chr11_-_65667809	2.759		FOSL1	FOS-like antigen 1
chr4_+_108745718	2.758	NM_001136258	SGMS2	sphingomyelin synthase 2
chr5_-_57755787	2.735	NM_001252226 NM_006622	PLK2	polo-like kinase 2
chr19_+_36208917	2.734	NM_014727	MLL4	myeloid/lymphoid or mixed-lineage leukemia 4
chr10_-_77161539	2.727		ZNF503	zinc finger protein 503
chr5_-_11904127	2.688		CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr19_+_49376488	2.682		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr19_-_1848359	2.681		REXO1	REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr10_+_104404195	2.678	NM_030912	TRIM8	tripartite motif containing 8
chr19_-_47734215	2.668	NM_014417	BBC3	BCL2 binding component 3
chr15_-_61521416	2.629		RORA	RAR-related orphan receptor A
chr19_+_45504686	2.619	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr22_+_50354428	2.599		PIM3	pim-3 oncogene
chr16_-_54319966	2.570		IRX3	iroquois homeobox 3
chr19_-_55628780	2.566	NM_017607	PPP1R12C	protein phosphatase 1, regulatory subunit 12C
chr19_+_45971249	2.544	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr18_-_74207145	2.536	NM_014643	ZNF516	zinc finger protein 516
chr19_+_4969123	2.531	NM_015015	KDM4B	lysine (K)-specific demethylase 4B
chr11_+_46299554	2.523		CREB3L1	cAMP responsive element binding protein 3-like 1
chr1_-_33430285	2.517	NM_001127361 NM_153341	RNF19B	ring finger protein 19B
chr16_-_75272524	2.465		BCAR1	breast cancer anti-estrogen resistance 1
chr19_+_36209125	2.451		MLL4	myeloid/lymphoid or mixed-lineage leukemia 4
chr7_+_1581072	2.448		MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr5_+_179248089	2.441		SQSTM1	sequestosome 1
chr9_-_86432546	2.433	NM_001135953 NM_025211	GKAP1	G kinase anchoring protein 1
chr12_-_96184510	2.432	NM_021229	NTN4	netrin 4
chr22_+_38599026	2.424	NM_001161573	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr22_+_50354139	2.417	NM_001001852	PIM3	pim-3 oncogene
chr9_+_35605614	2.406		TESK1	testis-specific kinase 1
chr3_-_134093235	2.394	NM_016201	AMOTL2	angiomotin like 2
chr16_+_1203240	2.373	NM_001005407 NM_021098	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr5_+_179247841	2.363	NM_003900	SQSTM1	sequestosome 1
chrX_+_49126299	2.360	NM_001184745 NM_033215	PPP1R3F	protein phosphatase 1, regulatory subunit 3F
chrX_+_152953751	2.346	NM_001142805 NM_005629	SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr20_+_4129466	2.346		SMOX	spermine oxidase
chr15_-_61521478	2.334	NM_134261	RORA	RAR-related orphan receptor A
chr10_-_32636084	2.329	NM_025209	EPC1	enhancer of polycomb homolog 1 (Drosophila)
chr14_+_75745480	2.298	NM_005252	FOS	FBJ murine osteosarcoma viral oncogene homolog
chrX_+_153686620	2.292	NM_017514	PLXNA3	plexin A3
chr11_-_63536112	2.292	NM_001144936	C11orf95	chromosome 11 open reading frame 95
chr1_+_223900328	2.276		CAPN2	calpain 2, (m/II) large subunit
chr1_+_32827797	2.272	NM_052841	TSSK3	testis-specific serine kinase 3
chr11_-_61684981	2.269	NM_013401	RAB3IL1	RAB3A interacting protein (rabin3)-like 1
chr5_+_179247911	2.268		SQSTM1	sequestosome 1
chr1_+_212782103	2.263		ATF3	activating transcription factor 3
chr1_+_46269283	2.257	NM_015112	MAST2	microtubule associated serine/threonine kinase 2
chr1_-_33815498	2.254	NM_004427	PHC2	polyhomeotic homolog 2 (Drosophila)
chr16_-_75285383	2.237	NM_001170717 NM_014567	BCAR1	breast cancer anti-estrogen resistance 1
chr11_+_46299161	2.227	NM_052854	CREB3L1	cAMP responsive element binding protein 3-like 1
chr2_-_73340073	2.225	NM_015470	RAB11FIP5	RAB11 family interacting protein 5 (class I)
chr1_-_33815411	2.213		PHC2	polyhomeotic homolog 2 (Drosophila)
chr19_+_35491329	2.208		GRAMD1A	GRAM domain containing 1A
chr8_-_144512601	2.189	NM_201589	MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr22_+_31489343	2.184		SMTN	smoothelin
chr9_+_35605339	2.174		TESK1	testis-specific kinase 1
chr12_+_133067156	2.166	NM_001142641	FBRSL1	fibrosin-like 1
chr12_+_110152186	2.158	NM_032829	C12orf34	chromosome 12 open reading frame 34
chr7_+_101460881	2.151	NM_181552	CUX1	cut-like homeobox 1
chr4_+_79472851	2.139		ANXA3	annexin A3
chr8_-_29207795	2.123	NM_001394	DUSP4	dual specificity phosphatase 4
chr19_-_46389307	2.123	NM_015649	IRF2BP1	interferon regulatory factor 2 binding protein 1
chr1_-_224033673	2.119	NM_001031685 NM_005426	TP53BP2	tumor protein p53 binding protein, 2
chr19_-_344778	2.117	NM_017550	MIER2	mesoderm induction early response 1, family member 2
chr18_-_48723689	2.113		MEX3C	mex-3 homolog C (C. elegans)
chr1_-_156675237	2.106	NM_001878 NM_001199723	CRABP2	cellular retinoic acid binding protein 2
chr22_-_20792107	2.102	NM_153334 NM_182895	SCARF2	scavenger receptor class F, member 2
chr11_-_67141008	2.095	NM_013246	CLCF1	cardiotrophin-like cytokine factor 1
chr20_+_51589752	2.086		TSHZ2	teashirt zinc finger homeobox 2
chr9_-_37576248	2.080	NM_012166	FBXO10	F-box protein 10
chr10_-_100027943	2.079	NM_032211	LOXL4	lysyl oxidase-like 4
chrX_+_49126326	2.077		PPP1R3F	protein phosphatase 1, regulatory subunit 3F
chr16_+_30675777	2.066	NM_001105079	FBRS	fibrosin
chr2_-_73340058	2.066		RAB11FIP5	RAB11 family interacting protein 5 (class I)
chr5_+_179247903	2.065		SQSTM1	sequestosome 1
chr1_-_224033603	2.061		TP53BP2	tumor protein p53 binding protein, 2
chr15_+_90544608	2.056	NM_198526	ZNF710	zinc finger protein 710
chr2_-_73339911	2.056		RAB11FIP5	RAB11 family interacting protein 5 (class I)
chr2_+_28616360	2.050		FOSL2	FOS-like antigen 2
chr14_+_55034633	2.044		SAMD4A	sterile alpha motif domain containing 4A
chr16_+_30406711	2.031	NM_152652	ZNF48	zinc finger protein 48
chr3_-_169482847	2.029		TERC	telomerase RNA component
chr9_+_35605449	2.029		TESK1	testis-specific kinase 1
chr6_+_157099262	2.027		ARID1B	AT rich interactive domain 1B (SWI1-like)
chr17_-_74497406	2.016	NM_024599	RHBDF2	rhomboid 5 homolog 2 (Drosophila)
chr2_+_205410716	2.013		PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chr5_-_39425030	2.012		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr5_-_11903964	2.006	NM_001332	CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr6_+_157099873	2.005		ARID1B	AT rich interactive domain 1B (SWI1-like)
chr1_+_157963310	2.000		KIRREL	kin of IRRE like (Drosophila)
chr10_-_32635842	1.993		EPC1	enhancer of polycomb homolog 1 (Drosophila)
chr8_+_81398416	1.992	NM_001105539 NM_023929	ZBTB10	zinc finger and BTB domain containing 10
chr5_-_39424930	1.986		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr7_+_150076405	1.986	NM_173680	ZNF775	zinc finger protein 775
chr22_+_31487315	1.983		SMTN	smoothelin
chr12_-_96184346	1.974		NTN4	netrin 4
chr15_+_40733302	1.971	NM_014952	BAHD1	bromo adjacent homology domain containing 1
chr2_+_220408352	1.963		TMEM198	transmembrane protein 198
chr16_-_68002455	1.963	NM_001145961 NM_001145962 NM_005072	SLC12A4	solute carrier family 12 (potassium/chloride transporters), member 4
chr19_+_10828813	1.961		DNM2	dynamin 2
chr4_+_109088677	1.940		LOC641518	uncharacterized LOC641518
chr11_-_78128852	1.938	NM_080491	GAB2	GRB2-associated binding protein 2
chr8_+_128806720	1.937		PVT1	Pvt1 oncogene (non-protein coding)
chr14_+_67999915	1.937	NM_020715	PLEKHH1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr12_-_112037024	1.931		ATXN2	ataxin 2
chr16_+_30676098	1.927		FBRS	fibrosin
chr11_+_64692052	1.922	NM_006244	PPP2R5B	protein phosphatase 2, regulatory subunit B', beta
chr9_+_139971938	1.919	NM_207309	UAP1L1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr17_-_63557615	1.910	NM_004655	AXIN2	axin 2
chr12_-_51611476	1.909		POU6F1	POU class 6 homeobox 1
chr22_+_38598065	1.908		MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr1_-_247494990	1.905	NM_032752	ZNF496	zinc finger protein 496
chr11_-_63933493	1.902	NM_014067	MACROD1	MACRO domain containing 1
chr19_+_13263890	1.897		IER2	immediate early response 2
chr1_+_178063237	1.896		RASAL2	RAS protein activator like 2
chr2_+_205410465	1.894	NM_057177 NM_152526 NM_205863	PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chr16_-_54320328	1.892		IRX3	iroquois homeobox 3
chr17_-_36762105	1.892	NM_025248	SRCIN1	SRC kinase signaling inhibitor 1
chr1_+_45266035	1.892	NM_004073	PLK3	polo-like kinase 3
chr7_+_73082157	1.885	NM_001077621	VPS37D	vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr1_-_214724844	1.879		PTPN14	protein tyrosine phosphatase, non-receptor type 14
chrX_-_108868250	1.877	NM_012282	KCNE1L	KCNE1-like
chr19_-_1863425	1.875		KLF16	Kruppel-like factor 16
chr1_+_45265896	1.869		PLK3	polo-like kinase 3
chr5_-_39425297	1.862	NM_001244871 NM_001343	DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr12_+_93964801	1.861		SOCS2	suppressor of cytokine signaling 2
chr7_+_1580009	1.855		MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr17_-_43394326	1.852	NM_003954	MAP3K14	mitogen-activated protein kinase kinase kinase 14
chr20_-_43729607	1.851	NM_002251	KCNS1	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
chr5_+_14143287	1.851	NM_007118	TRIO	triple functional domain (PTPRF interacting)
chr19_+_39897457	1.849	NM_003407	ZFP36	zinc finger protein 36, C3H type, homolog (mouse)
chr4_-_967327	1.839	NM_001347	DGKQ	diacylglycerol kinase, theta 110kDa
chr17_-_63557764	1.837		AXIN2	axin 2
chr1_+_178063302	1.822		RASAL2	RAS protein activator like 2
chr6_+_157099203	1.822
chr1_-_228135587	1.817	NM_003395	WNT9A	wingless-type MMTV integration site family, member 9A
chr16_-_75299713	1.816	NM_001170720 NM_001170714 NM_001170718	BCAR1	breast cancer anti-estrogen resistance 1
chr1_+_86046434	1.815	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr11_+_13984139	1.814	NM_006108	SPON1	spondin 1, extracellular matrix protein
chr4_+_79472741	1.813	NM_005139	ANXA3	annexin A3
chr7_-_152133071	1.809	NM_170606	MLL3	myeloid/lymphoid or mixed-lineage leukemia 3
chr10_-_3827205	1.806		KLF6	Kruppel-like factor 6
chr9_-_38069082	1.806		SHB	Src homology 2 domain containing adaptor protein B
chr9_-_29738	1.797	NM_182905	WASH1	WAS protein family homolog 1
chr1_-_156470538	1.795		MEF2D	myocyte enhancer factor 2D
chr19_-_4065467	1.791		ZBTB7A	zinc finger and BTB domain containing 7A
chr17_-_17399494	1.785	NM_001199989 NM_016084	RASD1	RAS, dexamethasone-induced 1
chr22_-_41032623	1.779		MKL1	megakaryoblastic leukemia (translocation) 1
chr9_+_99212379	1.774	NM_014282	HABP4	hyaluronan binding protein 4
chr14_-_21566497	1.768		ZNF219	zinc finger protein 219
chr1_+_223900212	1.766		CAPN2	calpain 2, (m/II) large subunit
chr12_+_133195365	1.762	NM_012226 NM_016318 NM_170682 NM_170683 NM_174872 NM_174873	P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2
chr2_-_145275086	1.755		ZEB2	zinc finger E-box binding homeobox 2
chr16_+_30406432	1.752	NM_001214909	ZNF48	zinc finger protein 48
chr19_-_460995	1.751	NM_012435	SHC2	SHC (Src homology 2 domain containing) transforming protein 2
chr20_+_4129409	1.750	NM_175839 NM_175840 NM_175841 NM_175842	SMOX	spermine oxidase
chr5_+_172068188	1.749	NM_001142651	NEURL1B	neuralized homolog 1B (Drosophila)
chr19_-_4066739	1.747	NM_015898	ZBTB7A	zinc finger and BTB domain containing 7A
chr13_+_73633097	1.747	NM_001730	KLF5	Kruppel-like factor 5 (intestinal)
chr3_+_49591897	1.743	NM_003458	BSN	bassoon (presynaptic cytomatrix protein)
chr6_+_36098261	1.742	NM_002754	MAPK13	mitogen-activated protein kinase 13
chr6_-_44233244	1.738		NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr2_+_171571800	1.737	NM_001003845	SP5	Sp5 transcription factor

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.88	3.90e-13	GO:0031323	regulation of cellular metabolic process
1.92	5.58e-13	GO:0060255	regulation of macromolecule metabolic process
1.87	1.61e-12	GO:0080090	regulation of primary metabolic process
1.51	3.14e-12	GO:0050794	regulation of cellular process
1.47	6.75e-12	GO:0050789	regulation of biological process
1.77	1.53e-11	GO:0019222	regulation of metabolic process
2.05	3.79e-11	GO:0048522	positive regulation of cellular process
1.97	1.02e-10	GO:0048518	positive regulation of biological process
2.06	4.11e-10	GO:0051252	regulation of RNA metabolic process
1.41	4.76e-10	GO:0065007	biological regulation
1.96	9.57e-10	GO:0010468	regulation of gene expression
1.89	7.28e-09	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.93	1.02e-08	GO:0010556	regulation of macromolecule biosynthetic process
1.94	1.07e-08	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.84	5.05e-08	GO:0051171	regulation of nitrogen compound metabolic process
1.84	7.54e-08	GO:0009889	regulation of biosynthetic process
1.84	8.31e-08	GO:0031326	regulation of cellular biosynthetic process
1.95	1.12e-07	GO:0006355	regulation of transcription, DNA-dependent
1.82	3.63e-06	GO:0048519	negative regulation of biological process
1.86	7.10e-06	GO:0048523	negative regulation of cellular process
1.87	1.23e-05	GO:0030154	cell differentiation
1.62	1.28e-05	GO:0007275	multicellular organismal development
2.05	1.32e-05	GO:0009653	anatomical structure morphogenesis
1.58	1.41e-05	GO:0032502	developmental process
2.35	1.51e-05	GO:0006357	regulation of transcription from RNA polymerase II promoter
2.22	1.58e-05	GO:0010604	positive regulation of macromolecule metabolic process
2.19	1.76e-05	GO:0031325	positive regulation of cellular metabolic process
2.56	1.95e-05	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.64	2.45e-05	GO:0048856	anatomical structure development
1.96	3.78e-05	GO:0023051	regulation of signaling
1.82	4.40e-05	GO:0048869	cellular developmental process
2.48	4.74e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
2.10	4.84e-05	GO:0051239	regulation of multicellular organismal process
2.11	5.62e-05	GO:0009893	positive regulation of metabolic process
1.87	5.94e-05	GO:0048583	regulation of response to stimulus
2.64	8.84e-05	GO:0001932	regulation of protein phosphorylation
1.58	1.11e-04	GO:0007165	signal transduction
1.54	1.38e-04	GO:0023052	signaling
2.55	1.55e-04	GO:0042325	regulation of phosphorylation
9.03	1.65e-04	GO:0001704	formation of primary germ layer
1.64	1.90e-04	GO:0048731	system development
2.28	2.12e-04	GO:0050793	regulation of developmental process
1.97	2.66e-04	GO:0009966	regulation of signal transduction
2.47	3.29e-04	GO:0019220	regulation of phosphate metabolic process
2.47	3.29e-04	GO:0051174	regulation of phosphorus metabolic process
2.51	3.42e-04	GO:0051254	positive regulation of RNA metabolic process
2.31	3.46e-04	GO:0031328	positive regulation of cellular biosynthetic process
2.28	5.55e-04	GO:0009891	positive regulation of biosynthetic process
2.37	7.16e-04	GO:0010557	positive regulation of macromolecule biosynthetic process
2.77	8.74e-04	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
2.42	1.21e-03	GO:0010628	positive regulation of gene expression
2.44	1.37e-03	GO:0007167	enzyme linked receptor protein signaling pathway
2.48	1.38e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.76	1.38e-03	GO:0048513	organ development
1.93	1.51e-03	GO:0035556	intracellular signal transduction
2.68	1.78e-03	GO:0043549	regulation of kinase activity
2.35	2.24e-03	GO:0009790	embryo development
2.69	2.33e-03	GO:0045859	regulation of protein kinase activity
2.34	2.51e-03	GO:0009890	negative regulation of biosynthetic process
2.80	2.54e-03	GO:0007243	intracellular protein kinase cascade
2.80	2.54e-03	GO:0023014	signal transduction via phosphorylation event
2.58	3.67e-03	GO:0051338	regulation of transferase activity
2.34	3.75e-03	GO:0045595	regulation of cell differentiation
2.33	4.04e-03	GO:0031327	negative regulation of cellular biosynthetic process
2.36	4.15e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
2.65	5.06e-03	GO:0048646	anatomical structure formation involved in morphogenesis
1.83	5.10e-03	GO:0007399	nervous system development
2.41	5.22e-03	GO:0010629	negative regulation of gene expression
2.00	6.55e-03	GO:0010941	regulation of cell death
2.00	7.62e-03	GO:0042981	regulation of apoptosis
1.42	9.20e-03	GO:0051716	cellular response to stimulus
2.16	9.49e-03	GO:0031399	regulation of protein modification process
1.99	9.55e-03	GO:0043067	regulation of programmed cell death
2.33	1.08e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.47	1.28e-02	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
2.41	1.44e-02	GO:0051253	negative regulation of RNA metabolic process
2.06	1.58e-02	GO:0006351	transcription, DNA-dependent
2.96	1.60e-02	GO:0045860	positive regulation of protein kinase activity
8.43	2.27e-02	GO:0001707	mesoderm formation
2.72	2.41e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.95	2.50e-02	GO:0032268	regulation of cellular protein metabolic process
2.38	2.61e-02	GO:0045892	negative regulation of transcription, DNA-dependent
2.86	2.70e-02	GO:0033674	positive regulation of kinase activity
2.68	3.05e-02	GO:0048598	embryonic morphogenesis
2.11	3.45e-02	GO:2000026	regulation of multicellular organismal development
7.73	4.16e-02	GO:0045768	positive regulation of anti-apoptosis
7.73	4.16e-02	GO:0048332	mesoderm morphogenesis
2.77	4.25e-02	GO:0051347	positive regulation of transferase activity
2.35	4.36e-02	GO:0010942	positive regulation of cell death
2.50	4.45e-02	GO:0032583	regulation of gene-specific transcription
2.23	4.68e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.97	4.70e-02	GO:0048468	cell development
1.93	4.93e-02	GO:0009892	negative regulation of metabolic process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.41	7.97e-06	GO:0005634	nucleus
1.18	1.14e-05	GO:0005622	intracellular
1.17	4.99e-04	GO:0044424	intracellular part
5.03	5.63e-03	GO:0014069	postsynaptic density

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
2.51	1.49e-08	GO:0030528	transcription regulator activity
2.53	1.63e-08	GO:0001071	nucleic acid binding transcription factor activity
2.53	1.63e-08	GO:0003700	sequence-specific DNA binding transcription factor activity
1.86	7.30e-08	GO:0003677	DNA binding
2.72	6.05e-07	GO:0043565	sequence-specific DNA binding
1.61	4.92e-06	GO:0003676	nucleic acid binding
1.17	5.14e-05	GO:0005488	binding
1.70	3.28e-04	GO:0008270	zinc ion binding
3.20	3.31e-04	GO:0008134	transcription factor binding
3.61	8.88e-04	GO:0019901	protein kinase binding
2.97	1.17e-03	GO:0016563	transcription activator activity
1.60	1.37e-03	GO:0046914	transition metal ion binding
3.26	2.19e-03	GO:0019900	kinase binding
1.26	2.82e-03	GO:0005515	protein binding
15.28	3.30e-03	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
7.07	4.45e-03	GO:0046332	SMAD binding
14.19	5.02e-03	GO:0033549	MAP kinase phosphatase activity
2.78	8.12e-03	GO:0016564	transcription repressor activity
2.12	1.41e-02	GO:0046983	protein dimerization activity
2.37	2.06e-02	GO:0004674	protein serine/threonine kinase activity
1.37	2.60e-02	GO:0046872	metal ion binding
1.35	4.30e-02	GO:0043169	cation binding
1.35	4.79e-02	GO:0043167	ion binding